Immune Peptides

KPV (Lys-Pro-Val)

Catalog #: KPV

KPV is the C-terminal tripeptide of α-MSH that retains potent anti-inflammatory activity via NF-κB inhibition — without melanocortin receptor-mediated pigmentation. Studied in IBD and mucosal immunity models.

Catalog Number KPV
Sequence Lys-Pro-Val (α-MSH residues 11-13)
Molecular Weight ~342.4 Da
Mechanism NF-κB inhibition (receptor-independent)

Available SKUs

Model Specification MOQ
KPV5 5mg / 10ml 1 vial
KPV10 10mg / 10ml 1 vial
Ships within 5-7 business days
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Product Overview

KPV is the C-terminal tripeptide of α-MSH that retains potent anti-inflammatory activity via NF-κB inhibition — without melanocortin receptor-mediated pigmentation. Studied in IBD and mucosal immunity models.

Research Applications

  • Smallest known anti-inflammatory peptide from α-MSH
  • Inhibits NF-κB nuclear translocation
  • No melanocortin receptor-dependent pigmentation effects
  • Transported via PepT1 across intestinal epithelium
  • Extensively studied in IBD and colitis research models

Key Features

  • Promotes M2 macrophage polarization
  • ≥99% purity confirmed by RP-HPLC and ESI-MS
  • For laboratory research use only

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Catalog Number KPV
Sequence Lys-Pro-Val (α-MSH residues 11-13)
Molecular Weight ~342.4 Da
Mechanism NF-κB inhibition (receptor-independent)
Transport PepT1 (SLC15A1) in intestinal epithelium
Form Lyophilized powder
Purity ≥99% (RP-HPLC)
Storage -20°C, desiccated

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