Hormone Peptides

Melanotan 1 (Afamelanotide)

Catalog #: MT1

MT-1 is a superpotent MC1R-selective α-MSH analog with Nle4/D-Phe7 modifications. 100× more potent than native α-MSH for melanocyte biology and photoprotection research.

Catalog Number MT1
Sequence Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
Modifications Nle4 (oxidation-resistant) + D-Phe7 (enhanced binding)
Primary Target MC1R (Gs-coupled GPCR)

Available SKUs

Model Specification MOQ
MT1-5 5mg / 10ml 1 vial
Ships within 5-7 business days
Certificate of Analysis included
Quality guaranteed

Product Overview

MT-1 is a superpotent MC1R-selective α-MSH analog with Nle4/D-Phe7 modifications. 100× more potent than native α-MSH for melanocyte biology and photoprotection research.

Research Applications

  • Superpotent MC1R-selective α-MSH analog (~100× native potency)
  • Nle4 + D-Phe7 modifications for stability and binding
  • Drives eumelanin synthesis via MITF/tyrosinase pathway
  • MC1R-selective: minimal MC3R/MC4R cross-reactivity vs. MT-2
  • Enhances NER DNA repair capacity via PKA/ATR/XPC

Key Features

  • ≥99% purity confirmed by RP-HPLC and ESI-MS
  • For laboratory research use only

Technical Support

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OEM Services

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Catalog Number MT1
Sequence Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
Modifications Nle4 (oxidation-resistant) + D-Phe7 (enhanced binding)
Primary Target MC1R (Gs-coupled GPCR)
Molecular Weight ~1646.9 Da
Form Lyophilized powder
Purity ≥99% (RP-HPLC)
Storage -20°C, desiccated

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