Anti-aging Peptides

PNC-27

Catalog #: PNC27

PNC-27 is a chimeric peptide combining a p53-derived HDM2-binding domain with a membrane-penetrating leader sequence. Selectively targets surface HDM2 on transformed cells for cancer biology research.

Catalog Number PNC27
Design Chimeric: p53(12-26) + membrane leader
Target Surface-expressed HDM2
Mechanism Membrane pore formation → necrotic lysis

Available SKUs

Model Specification MOQ
PNC27-5 5mg / 10ml 1 vial
PNC27-10 10mg / 10ml 1 vial
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Certificate of Analysis included
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Product Overview

PNC-27 is a chimeric peptide combining a p53-derived HDM2-binding domain with a membrane-penetrating leader sequence. Selectively targets surface HDM2 on transformed cells for cancer biology research.

Research Applications

  • Chimeric peptide with p53-derived HDM2-binding domain
  • Selectively targets surface HDM2 on transformed cells
  • Normal cells spared in co-culture experiments
  • Independent of intracellular p53 status
  • Published in breast, pancreatic, leukemia, and melanoma models

Key Features

  • ≥99% purity confirmed by RP-HPLC and ESI-MS
  • For laboratory research use only

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OEM Services

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Catalog Number PNC27
Design Chimeric: p53(12-26) + membrane leader
Target Surface-expressed HDM2
Mechanism Membrane pore formation → necrotic lysis
Selectivity Transformed cells only (normal cells spared)
Form Lyophilized powder
Purity ≥99% (RP-HPLC)
Storage -20°C, desiccated

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